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Marker Discovery Could Mean More Effective Mesothelioma Treatment

By Katie Kelley

Republish: EasyPublish™ Published: 18Feb2011 Word count: 446 Viewed: 166 time(s) Get Free Content For Your Site

Researchers at the Asbestos Disease Research Institute in Australia have discovered a "tumor marker" which could help oncologists provide more precisely tailored treatment options to mesothelioma patients. Mesothelioma (formally known as malignant mesothelioma) is a rare form of cancer that receives approximately 2,000 to 3,000 new diagnoses each year.

Researcher Nico Van Zandwuck, said a bloodborne marking factor can help determine how aggressive an individual patient's form of mesothelioma will be, and how it will respond to various treatment options. This information could help oncologists adjust treatment for particular patients with minimal side effects. However, the patient must be physically able to tolerate the treatment.

In addition, therapeutic advances in surgery, chemotherapy, and radiation therapy now allow oncologists to expand treatment options into novel areas. For example, radiation therapy- once seen as largely palliative, meaning treatment that improved breathing and pain- can now be used to re-treat an area that once saw the treatment of traditional surgery to remove cancerous tissue.

Barry Robson, a former Australian dock worker who handled his fair share of asbestos and president of the Asbestos Disease Foundation of Australia, commended the Asbestos Disease Research Institute for its quick (18-month) identification of the marker. He also noted the agency's importance in ongoing mesothelioma treatment, where the period of death from diagnosis is approximately 135 days.

Mesothelioma tissues are those that surround and protect the body's vital organs. These organs include the lungs, the heart, and the abdominal organs. Peritoneal mesothelioma, or mesothelioma cancer surrounding the abdominal regions, is the rarest form of mesothelioma and occurs in fewer than two percent of all mesothelioma cases.

Mesothelioma is an insidious cancer - individuals may inhale or ingest asbestos fibers while at work, at home, or at school. The disease lays dormant for many years- sometimes for up to 50 years. This is unfortunate as early and accurate diagnosis can make it easier to treat. There is currently no cure for the disease, but researchers are hopeful that new research like the studies that have been done at the Asbestos Disease Research Institute could greatly extend patients' lives. Those diagnosed during Stage II or later, when the cancer has metastasized, meaning the cancer has spread to other tissues and organs in the body, are only given about one year to live.

Diagnosis is usually confirmed through an MRI, CT scan, or X-ray. An X-ray will show pleural effusions, a classic manifestation of mesothelioma. Tissue masses indicating a tumor or scarring from asbestos can also alert physicians of a possible mesothelioma diagnosis. Mesothelioma symptoms include: pain in the chest or abdominal region, persistent coughing, shortness of breath, or fatigue.

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